The COVID-19 pandemic created an urgent need to develop preventive vaccines to blunt the impact of the greatest global health crisis in a century. Two vaccines, both employing mRNA technology, were developed from bench to bedside in under one year…
Influenza viruses are one of the key pathogens causing acute respiratory infections in humans, which lead to significant economic burdens. From August 2023 to May 2024, hospitalized SARI cases were recruited from Shouguang People’s Hospital in Weifang, Shandong Province. Reverse…
BackgroundMetacognition is central to clinical diagnostic problem solving, yet few instructional models provide actionable guidance for embedding explicit metacognitive support into clinical training.ObjectiveThis study aimed to introduce and evaluate the Metacognition-Integrated Instruction for Novice Diagnostic (MIND) learning model, a structured…
IntroductionSince the Match was established in 1952, residency interviews in the United States were conducted in person. This abruptly changed in May 2020, when the Coalition for Physician Accountability mandated that programs conduct interviews virtually for the 2020-2021 application season.…
BackgroundVolleyball demands frequent explosive, stretch-shortening muscle actions that elevate the risk for exercise-induced muscle damage (EIMD) and delayed-onset muscle soreness (DOMS). Polyphenol-rich pomegranate juice (POMj) has been proposed to aid recovery, yet evidence in highly trained team-sport athletes is limited.…
Sepsis-induced acute kidney injury (S-AKI) is a common and serious complication in critically ill children with a poor prognosis, and its early and accurate prediction remains challenging due to the lack of reliable biomarkers. Urinary small-molecule metabolomics offers a promising…
This study develops a dual-level machine learning framework for risk stratification and phenotyping of hearing loss (HL) in patients with chronic kidney disease (CKD) using data from the National Health and Nutrition Examination Survey (NHANES). From a cohort of 3,402…
Continuous renal replacement therapy (CRRT) is widely used in critically ill patients, but filter clotting remains a common complication. Regional citrate anticoagulation (RCA) is recommended; however, its real-world effectiveness may depend on implementation quality. This single-center retrospective cohort study analyzed…
BackgroundClimate change poses a major threat to global health. Its synergistic interaction with non-communicable diseases (NCDs), responsible for 74% of global deaths, demands urgent, integrated action.ObjectivesThis study critically examines how transdisciplinary approaches can uncover and address structural determinants underpinning climate…
Peritoneal dialysis (PD) is a common treatment for end-stage renal disease, yet cardiovascular disease (CVD) remains a major cause of morbidity. Inadequate fluid management can elevate CVD risk, and bioelectrical impedance spectroscopy (BIS) is increasingly used to assess fluid status.…