The treatment of osteosarcoma has remained largely unchanged over the past decades. Its low incidence, predominantly affecting children and young adults, combined with marked biological heterogeneity, poses major challenges to the development of effective therapies, and currently approved regimens often…
The aim of this article is to analyse the motivations, expectations, and experiences of information exchange and contact among parties linked through donor conception of solo mothers who had their children with the help of assisted reproduction technology (ART) across…
Limited education and healthcare access are major contributors to Human Papillomavirus (HPV) vaccination disparities among African American adolescents. The Immunization Neighborhood (IN) involves enhanced communication and collaboration among providers to address people’s needs by expanding access points and education to…
BackgroundPseudomonas aeruginosa relies on antioxidant enzymes to withstand host-derived oxidative stress during infection. Here, we investigated the role of bacterial glutathione peroxidase (GPx) in survival and virulence of the PA14 strain under inflammatory conditions associated with hyperuricemia.MethodsWild-type (WT) and Δgpx…
Candidozyma auris (C. auris) is an emerging multidrug-resistant fungal pathogen with major global public health implications. However, the clinical characteristics, clade-specific genomic variation, resistance-associated SNP patterns, and transmission dynamics of C. auris in China remain insufficiently understood. We retrospectively analyzed…
BackgroundArtificial intelligence (AI) is increasingly integrated into healthcare, making AI literacy an essential competency for medical students. Existing assessments are often generic, lack validation in medical education, and are not grounded in learning theory. This study developed and validated the…
Broad-spectrum antibiotics, essential for sepsis management in critically ill patients, cause significant gut dysbiosis. Restoring gut microbiota may improve outcomes, but the efficacy of interventions like fecal microbiota transplantation (FMT) and probiotics in this setting remains underexplored. This study aims…
BackgroundPost-competition refeeding in physique athletes is poorly understood. We aimed to characterize physiological and psychological changes in natural physique athletes across contest preparation and a 12-week recovery period, and to explore the influence of post-competition refeeding strategies.MethodsNineteen natural physique athletes…
BackgroundCollegiate dancers face high training loads, aesthetic pressures, and limited access to nutritional resources, elevating their risk for low energy intake and micronutrient insufficiency. Although inadequate micronutrient intake has been documented, prior studies are largely limited to single sites, ballet-focused…
Artificial intelligence and machine learning (AI/ML) utilisation in Alaska Native and American Indian (AN/AI) healthcare presents an opportunity to address persistent health disparities and improve the well-being of Alaska Native communities. The 2025 Artificial Intelligence in Alaska Native Health Care…