ObjectiveTo identify plasma protein differences between type 2 diabetes mellitus (T2DM) patients with and without metabolic dysfunction-associated steatotic liver disease (MASLD), and to evaluate the diagnostic potential of X-prolyl aminopeptidase 3 (XPNPEP3) for identifying MASLD in T2DM patients.MethodsTwenty T2DM inpatients…
Background: Despite ongoing debate on the necessity of using the Continuous Traumatic Stress Response (CTSR) concept in contexts of repetitive threat – where the traditional post-traumatic stress disorder (PTSD) paradigm is insufficient [Goral, A., Feder-Bubis, P., Lahad, M., & Aharonson-Daniel,…
Background: North Korean defectors (NKDs), a predominantly trauma-exposed population, are at high risk for somatic symptoms. Unrecognized and untreated somatic symptoms can profoundly affect health and psychosocial functioning. Therefore, it is crucial to understand and address somatic symptoms in the…
Background: Afghan adolescents have been exposed to decades of war, displacement, and limited access to mental health care. Memory Training for Recovery-Adolescent Plus (METRA+) was developed to address posttraumatic stress (PTSD), depression, and social functioning through a brief, culturally adapted,…
BackgroundThe relationship of systemic immune-inflammation index (SII) with mortality in hyperlipidemic patients remains unknown. In the present work, we evaluated SII for its ability to predict mortality incidence and examined its relationship with mortality of hyperlipidemic individuals.MethodsAltogether 27,903 hyperlipidemic cases…
Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are rare, idiopathic, chronic cholestatic liver diseases that respond differently to limited medical therapies and often lead to liver transplantation. We examined the compositional and functional differences in the gut microbiome,…
AimDuring the recent global pandemic, nursing home (NH) residents were among the most vulnerable, yet empirical insights into how practitioners conceptualized and implemented infection control in NHs were limited. This study aimed to explore the ways in which interdisciplinary NH…
Hepatorenal syndrome-associated acute kidney injury (HRS-AKI) carries high short-term mortality. Prognosis is usually based on creatinine-defined AKI stage, but early creatinine trajectories may add information. In this retrospective cohort study (January 2019-September 2024), we included adults with cirrhosis fulfilling contemporary…
The 2023 American Heart Association Presidential Advisory introduced cardiovascular-kidney-metabolic (CKM) syndrome, but the mortality impact of „Weekend-Warrior“ (WW) physical activity in this population remains uncertain. Using data from 1,927 adults in the 2003-2006 NHANES with accelerometer-measured activity and CKM stages…
BackgroundThe link between long-term protein intake and muscle performance in older adults has been hard to define, partly because most studies rely on short dietary windows and are vulnerable to confounding and measurement noise. In this work, we attempted to…