Meningococcal vaccination of adolescents/young adults is recommended in various countries, including the United States (US). This phase 3b, observer-blind study (NCT04318548) evaluated the safety, reactogenicity, and immunogenicity of serogroup B vaccine, 4CMenB, and quadrivalent conjugate vaccine, MenACWY-CRM, when co-administered to…
ObjectivesThis study aimed to investigate the current level of clinical leadership among cardiovascular nurses and identify its associated factors.MethodsA multicentre cross-sectional study was conducted among 411 cardiovascular nurses from three tertiary hospitals in China between January and June 2025. Data…
BackgroundPolycythemia vera (PV) is a myeloproliferative neoplasm frequently complicated by thromboembolic events. However, data regarding thrombotic burden and long-term outcomes among Asian patients remain limited.Materials and methodsWe conducted a retrospective cohort study at a tertiary referral center to evaluate thromboembolic…
PurposeThis study aimed to compare the impact on inflammatory response, clinical efficacy, and safety between vancomycin-loaded polymethylmethacrylate (PMMA) and a combination of vancomycin-loaded PMMA with vancomycin sulfate calcium (PMMA-SC) in treating chronic osteomyelitis.MethodsA retrospective cohort study involved 244 patients with…
BackgroundPulmonary nodules are common on chest CT in bronchiectasis (BE) patients. This study identifies risk factors for nodule malignancy in BE patients with pulmonary nodules.MethodWe screened BE patients who underwent chest CT at Second Xiangya Hospital from Jan 1, 2019…
Background: Adverse life experiences evoke thoughts and emotions that may negatively affect adult refugees‘ language learning. This may significantly impact the ability to establish their lives in the resettlement country. However, little attention has been paid to adult refugee learners’…
Background: Post-traumatic stress disorder (PTSD) is one of the most common psychological consequences following road trauma (RT), leading to physical and psychological impairments.Objectives: This study aims to identify distinct PTSD trajectories following RT and examine their association with recovery outcomes.Methods:…
Background: Individuals with bipolar disorder are at increased risk of exposure to traumatic events and associated psychological distress, including affective, cognitive, physiological, and mood-related difficulties. Eye movement desensitisation and reprocessing (EMDR) targets unprocessed trauma memory networks underlying these difficulties; however,…
BackgroundIn general practice, symptom diagnoses are commonly used when patients seek care for symptoms in which no specific disease or disorder can be diagnosed. These diagnoses are prevalent, yet little is known about how they evolve or how General Practitioners…
Long-term outcomes of kidney allografts vary significantly among deceased donor kidney transplant recipients, and current prediction tools struggle to integrate comprehensive pre- and post-transplant factors. Extended longitudinal follow-up data beyond five years remains particularly scarce in kidney transplantation research despite…