To investigate the influence of probiotic supplementation on parameters of renal function, dogs with chronic kidney disease (CKD) received a commercial probiotic formulation containing Enterococcus lactis SF68 (n = 8) or placebo (n = 8) for 60 days. Gut microbiome was investigated by comparing with…
Contrast-induced acute kidney injury (CI-AKI), the third most common cause of hospital-acquired kidney injury, is associated with poor clinical outcomes, highlighting the need for accurate prediction. In this study, we used an electronic hospital monitoring system to retrospectively analyze 3,437…
ObjectivesLarge volumes of polyethylene glycol (PEG) solution reduce patient acceptance of colonoscopy. A prepackaged low-residue diet (PLRD; Clear-Through) may improve bowel cleansing and allow further PEG reduction. This exploratory randomized study evaluated whether PLRD permits decreased PEG with ascorbic acid…
BackgroundPost-endoscopic retrograde cholangiopancreatography (post-ERCP) pancreatitis (PEP) is the most severe adverse event associated with ERCP. Although numerous studies have identified risk factors for PEP, the role of genetic background in its development remains unexplored. The present study investigated the association…
IntroductionThe selection of an optimal maintenance agent in diffuse large B-cell lymphoma (DLBCL) continues to pose a significant clinical challenge. This study aims to evaluate the prognostic impact of maintenance therapy (MT) in DLBCL.MethodsWe conducted a retrospective analysis of data…
The gut microbiome is increasingly recognized as a fundamental regulator of metabolic health, shaping energy balance, insulin sensitivity, inflammatory tone, and inter-organ communication through a broad spectrum of microbial metabolites that engage host signaling pathways. In this review, we synthesize…
Cryptococcus neoformans is responsible for pulmonary cryptococcosis and life-threatening cryptococcal meningitis, particularly in immunocompromised individuals. Despite its high mortality rate and the diagnostic challenges, current antifungal therapies are hampered by limitations such as side effects and the emergence of drug…
BackgroundNuclear factor kappa B (NF-κB) is a key regulator of inflammatory responses involved in chronic inflammatory diseases. Bioactive compounds from ginger (Zingiber officinale) inhibit NF-κB signaling but are limited by poor bioavailability. This systematic review aimed to evaluate experimental evidence…
The COVID-19 pandemic created an urgent need to develop preventive vaccines to blunt the impact of the greatest global health crisis in a century. Two vaccines, both employing mRNA technology, were developed from bench to bedside in under one year…
Influenza viruses are one of the key pathogens causing acute respiratory infections in humans, which lead to significant economic burdens. From August 2023 to May 2024, hospitalized SARI cases were recruited from Shouguang People’s Hospital in Weifang, Shandong Province. Reverse…