ObjectiveFecal incontinence (FI) is a common and distressing long-term complication following minimally invasive surgery (MIS) for colorectal cancer (CRC), yet the role of modifiable lifestyle factors remains unclear. This study examined the associations between dietary habits (red meat, fiber-rich foods,…
BackgroundThe coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its evolving variants, continues to challenge global efforts to control its spread. Ongoing mutations may enhance transmissibility or lead to breakthrough infections, making immune…
Glioblastoma (GBM) therapy remains one of the most formidable challenges in oncology because of the blood-brain barrier (BBB), immunosuppressive tumor microenvironment, and drug resistance. To overcome these challenges, we designed engineered angiopep-2-decorated bacterial outer membrane vesicles for targeted drug delivery…
Chronic hepatitis B virus (HBV) infection in endemic regions often begins in infancy and persists throughout life. Although anti-HBs antibody levels may decline over time, long-term protection usually remains. The me chanisms underlying this sustained protection are not fully understood.…
BackgroundFriendship is recognized as vital for mental health and quality of life. It encompasses both protective and challenging aspects, constituting a relational and existential dimension in human life. Despite extensive research on the significance of friendship, less is known about…
BackgroundTo develop and validate an integrated radiopathomics nomogram combining multiphase CT images, H&E-stained slides, and clinicopathological variables for predicting microvascular patterns (MVPs) in non-small cell lung cancer (NSCLC).MethodsWe retrospectively included consecutive surgically resected NSCLC patients from two centers (n = 258). Patients…
Acinetobacter baumannii (A. baumannii) has emerged as a major global healthcare threat, ranking among the leading causes of both hospital-acquired and community-acquired infections. Its extensive antibiotic resistance complicates treatment, underscoring the need for therapeutic targets that elicit robust immune responses.…
Mental health problems are increasing among adolescents, where stress, screen time, social media and sleep deprivation are contributing factors. The aim of this study was to explore adolescents‘ understanding and self-reporting of health for further development of the screening tool…
Background: Episiotomy is considered a protective intervention when used selectively rather than routinely. Although current obstetric practice no longer recommends routine episiotomy, data on its use remain limited, particularly in Lebanon.Objective: This study evaluated the prevalence, predictors, and maternal outcomes…
Patients with Clostridioides difficile infection have high colonic levels of primary bile acids, which are potent germinators of Clostridioides difficile. Several studies have suggested that re-establishing a normal bile acid composition is a key factor in fecal microbiota transplantation (FMT)…