BackgroundNurses working in emergency departments encounter a wide range of professional challenges stemming from the inherently complex, unpredictable, and high-intensity nature of emergency care. These challenges exert a considerable influence on their clinical performance. Among the most critical factors, workload…
BackgroundDelirium is a serious hospital complication with long-lasting and life-threatening consequences and high healthcare costs. Despite decades of evidence, tools, and guidelines, delirium remains under-recognised and under-treated.ObjectiveTo examine alignment between policy and practice for delirium risk identification, screening, and assessment…
Background: Artificial intelligence is increasingly transforming healthcare delivery and health professions education, particularly in clinical skills training and simulation-based learning environments. This transformation necessitates an evaluation of the readiness of future nurses. However, limited evidence exists regarding nursing students‘ readiness…
ObjectivesAdvances in chemotherapy have increased survival in biliary tract cancer patients, and reports of the effectiveness of neoadjuvant therapy are emerging. Accordingly, developing optimal drainage strategies under chemotherapy is important. We aimed to clarify suitable drainage methods and assess the…
ObjectivesHistological subtype is an important pathological factor in risk stratification for lymph node metastasis (LNM) in T1 colorectal cancer (CRC); however, conventional predominant-type assessment may miss minor poorly differentiated components in T1b CRC. We aimed to develop a T1b-specific risk…
BackgroundWhile the Updated Sydney System classifies Helicobacter pylori density together with inflammatory scores, the clinical relevance of bacterial load remains uncertain. This study aimed to assess the association between histological H. pylori density and the severity of gastric inflammatory activity.MethodsWe…
Periprostatic adipose tissue (PPAT) is a potential factor closely associated with prostate cancer (PCa) development. This study aimed to introduce normalized PPAT thickness, a novel imaging biomarker, as a PCa predictor for patients within the diagnostic ‚double gray zone‘, defined…
Knee osteoarthritis (OA) is a prevalent, painful, degenerative disease lacking effective disease-modifying drugs. The rise in obesity has increased the prevalence of metabolic OA, underscoring the need for effective management to delay or prevent knee replacement. Prebiotics confer improvement in…
Respiratory syncytial virus (RSV) is a leading cause of pediatric lower respiratory tract infections, yet evidence on vaccine acceptance among Chinese pregnant and postpartum women remains limited. This study examines the willingness, preference and factors influencing neonatal RSV immunization among…
Depemokimab is a monoclonal antibody that targets interleukin-5 with enhanced binding affinity and an extended terminal elimination half‑life of 6-8 weeks. The unique pharmacodynamic features of depemokimab enable sustained suppression of type 2 inflammation with twice‑yearly subcutaneous dosing. This narrative review…