IntroductionRecent studies have shown that Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have significant potential to protect retinal ganglion cells (RGCs) function. Here, EVs were obtained from various MSCs, including dental pulp MSCs, trabecular meshwork MSCs, and bone marrow-derived clonal MSCs…
BackgroundPressure injuries contribute substantially to patient morbidity and healthcare costs. However, comprehensive analyses of their burden within the U.S. paediatric population are limited. As a cross-sectional database, the National Inpatient Sample permits estimation of hospitalization-based prevalence rather than true prevalence.…
IntroductionDespite the global shortage of nurses, there is limited literature that comprehensively maps interventions to support, stabilize, and enhance the nursing workforce.PurposeThis umbrella review aimed to identify structures, interventions, and health system arrangements that healthcare systems have put in place…
BackgroundCarnosine (β-alanine-L-histidine) is an endogenous dipeptide found in abundance in highly metabolic tissues such as skeletal muscle and the brain, where it is thought to play a role in intracellular buffering, and thereby, promote anaerobic glycolysis. Due to its perceived…
BackgroundThe effectiveness of the nursing workforce is critical for patient safety and quality of care, yet nurses often face high-stress environments that can foster negative psychosocial states. Although organizational cynicism and workplace alienation are recognized as important workplace concerns, their…
BackgroundPressure injuries, also known as pressure ulcers, remain a major global health problem, causing significant clinical, economic, and psychosocial burdens despite advances in prevention and treatment. While most research has focused on hospital-acquired cases, community-acquired pressure injuries are increasingly recognised,…
BackgroundSiblings of individuals with schizophrenia often assume caregiving roles as their parents age. However, the process by which the unaffected siblings balance their family life and their relationship with the affected sibling remains unclear.ObjectiveThis study aimed to clarify the process…
BackgroundSmoking is a major risk factor for several leading causes of death worldwide and is the primary cause of chronic obstructive pulmonary disease. Smoking cessation remains the only effective intervention to halt disease progression. Evidence on smoking cessation outcomes with…
Growth Differentiation Factor 9 (GDF9) is a key candidate gene in sheep breeding. Various mutations within GDF9 influence reproductive performance by affecting ovarian function and fertility traits in sheep. As no study has been conducted so far to explore GDF9…
ObjectiveThis study aimed to assess the reliability and identify sources of discrepancies to strengthen data governance and system integrity of the national forensic toxicology surveillance database from postmortem examinations called by the Forensic Drug Abuse Monitoring Network (FDAMN), Thailand.MethodsA facility-based…